New Method Tricks Cancer Cells Into Self-Destruction! 🎯

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Summary:

  1. Innovative Cancer Therapy
    Researchers at Stanford have developed a novel approach that tricks cancer cells into self-destructing by activating their natural cell death processes.

  2. Mechanism of Action
    The method involves artificially linking two proteins, BCL6 and CDK9, to switch on apoptosis-promoting genes that are usually suppressed by BCL6 in cancer cells.

  3. Promising Lab Results
    In laboratory tests, the new compound was highly effective at killing diffuse large B-cell lymphoma cells without causing significant toxicity to healthy cells.

  4. Targeted Specificity
    The technique specifically targets lymphoma cells, as BCL6 is primarily present in these cells, making the therapy potentially less harmful to other types of cells.

  5. Future Directions
    The researchers have co-founded Shenandoah Therapeutics to advance their findings toward clinical trials and explore similar compounds for targeting other cancer-driving proteins.

Read more at: Stanford Medicine

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